ASOKE WELLNESS SERVICE · 03
DFPP — Double Filtration Plasmapheresis
DFPP, or Double Filtration Plasmapheresis, is an advanced blood purification technology that filters toxins at the cellular level. Using a two-stage plasma filtration system, it separates waste products, harmful lipids (such as cholesterol and triglycerides), abnormal antibodies and inflammatory substances from the bloodstream — before returning the cleansed blood to the body.
How does DFPP work?
DFPP filters the blood in two layers. First the plasma — the liquid part of the blood — is separated from the other components, such as red blood cells, white blood cells and platelets. The separated plasma is then passed through a second filter to remove toxins, waste, allergens and unwanted proteins.
The DFPP Principle
- 01
Separate the plasma
- Blood passes through the first filter, which separates the plasma from the other blood components.
- 02
Filter the plasma
- The separated plasma is filtered again to remove toxins, waste and unwanted proteins.
- 03
Return clean plasma
- The filtered blood is returned to the body, replenished with clean, toxin-free plasma.
Who is DFPP suitable for?
- Those seeking overall health restoration — such as people experiencing fatigue and exhaustion, wanting to strengthen immunity, or preparing for PRP or stem cell therapy
- Those with immune-system conditions — such as rheumatoid arthritis, SLE, or autoimmune disease
- Those with blood vessel problems — such as arteriosclerosis or narrowed vessels
- Those with high blood lipid levels — such as hyperlipidemia or heart disease
- Those with high blood protein levels — such as hyperproteinemia
- Those with certain infections — such as HIV, hepatitis B and hepatitis C
Who should not undergo DFPP?
- People with bleeding disorders
- People with severe cardiovascular disease
- Women who are pregnant or breastfeeding
- People with chronic kidney failure
- People with severe infections
- People allergic to the medications or solutions used in DFPP — for example, egg or albumin allergy
Frequently asked questions — DFPP
How to prepare before DFPP
Before undergoing DFPP, you should:
- Inform your physician of underlying conditions, current medications, drug allergies and any important health information
- Undergo the physical examination and blood tests your physician requires to assess readiness — for example, a G6PD test
- Eat and drink adequately, unless instructed to fast
- Rest well before the procedure
- Wear comfortable clothing convenient for the procedure
- Allow enough time — DFPP may take several hours
- Follow your physician's instructions strictly
Preparation may differ from person to person, depending on your condition and your physician's treatment plan.
Which conditions can DFPP help treat?
DFPP (Double Filtration Plasmapheresis) is a therapy that filters specific substances out of the blood plasma — such as antibodies or large proteins. Physicians may consider it for certain patient groups, such as:
- Certain autoimmune diseases
- Certain immune-related neurological disorders
- Abnormally high levels of certain lipids or proteins in the blood
- Other diseases or conditions per medical indication and the physician's judgment
Caring for yourself after DFPP
After DFPP, you should:
- Drink plenty of water to help maintain the body's balance
- Rest adequately and avoid strenuous activity at first
- Watch for unusual symptoms — dizziness, fatigue, numbness, chills, or bleeding at the procedure site
- Care for the venipuncture site as instructed by the medical team
- Take prescribed medication and attend follow-up appointments per the treatment plan
How long does DFPP take?
Duration varies by individual — generally around 2–4 hours per session, depending on:
- The volume of blood and plasma to be filtered
- The patient's physical condition
- The physician's treatment plan
The number of sessions depends on your condition and your individual response to treatment.
Side effects and risks of DFPP
DFPP is a procedure that must be performed by an experienced medical team. Possible risks include:
- Dizziness, lightheadedness or fatigue
- Numbness or tingling, from changes in blood calcium levels
- Low blood pressure during the procedure
- Nausea or discomfort
- Bleeding or bruising at the venipuncture site
- Risks associated with vascular catheters, such as infection (when one is required)
If you notice unusual symptoms after the procedure, inform your physician or care team immediately for assessment and appropriate care.
“Filters viruses, waste, cholesterol, allergens and pollutants — for cleaner blood.”
